1.Aeberhard, K.I., Bruckmaier, R.M. and Blum, J.W. 2001. Metabolic, enzymatic and endocrine status in high-yielding dairy cows-Part 2. J. Vet. Med., 48: 111-127.

2.Barkema, H.W., Westrik, J.D., Van Keulen, K.A.S., Schukken, Y.H. and Brand A. 1994. The effects of lameness on reproductive performance, milk production and culling in Dutch Dairy Farms. Prev. Vet. Med., 20: 249–259.

3.Blowey, R.W., Phipps, R.A., Jones, K. and Barringer, A.J. 2000. A comparison of the effects of high fibre and high starch diets on hoof lesion score in multiparous dairy cows. In: Proceedings of XIth International Symposium on Disorders of the Ruminant Digit and III International Conference on Bovine Lameness, pp. 337-339

4.Baggott, D.G., Bunch, K.J. and Gill, K.R. 1988. Variations in some inorganic components and physical properties of claw keratin associated with claw disease in the British Friesian cow. Brit. Vet. J., 144: 534–542.

5.Baird, G.D. 1982. Primary ketosis in the high-producing dairy cow: clinical and subclinical disorders, treatment, prevention, and outlook. J. Dairy. Sci., 65: 1-10.

6.Bauman, D.E. and Currie, W.B. 1980. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy. Sci., 63: 1514-1529.

7.Bergsten, C. and Mulling Ch. K.W. 2004. Some reflections on research on bovine laminitis – aspects of clinical and fundamental research. In: Proceedings of the 13th International Symposium on Lameness in Ruminants. Maribor/Slovenia. pp: 53-60.

8.Bhadauria, Pragya., Lathwal, S.S., Jadoun, Y.S. and Bhadauria, S.S. 2012. Role of Biotin in Prevention of Lameness in Dairy Cattle-Review. Wayamba J of Anim Sci., pp. 635-646.

9.Blum, J.W., Kunz, P.L., Leuenberger, H., Gautschi, K. and Keller, M. 1983. Thyroid hormones, blood plasma metabolites and haematological parameters in relationship to milk yield in dairy cows. Anim. Prod., 36: 93-104.

10.Chapinal, N., Carson, M., Duffield, T.F., Capel, M., Godden, S., Overton, M., Santos, J.E.P. and LeBlanc, S.J. 2011. The association of serum metabolites with clinical disease during the transition period. J. Dairy Sci., 94: 4897-4903.

11.Collik, D.W., Ward., W.R. and Dobson, H. 1989. Associations between types of lameness and fertility. Vet. Rec., 125: 103- 106.

12.Campbell, J.R., Greenough, P.R., and Petrie, L. 2000. The effects of dietary biotin supplementation on vertical fissures of the claw wall in beef cattle. Can. Vet. J., 41: 690–694.

13.DaCosta Gomez, C., Al Masri, M., Steinberg, W. and Abel, H.J. 1998. Effect of varying hay/barley proportions on microbial biotin metabolism in the rumen simulating fermenter (RUSITEC). In: Proceedings of Society of Nutrition Physiology 7 (Abstr.).

14.Dann, H.M., Litherland, N.B., Underwood, J.P., Bionaz M., D’Angelo D., McFadden J.W. and Drackley, J. K. 2006. Diets during far-off and close-up dry periods affect periparturient metabolism and lactation in multiparous cows. J. Dairy Sci., 89: 3563-3577.

15.Demertizis, P.N. 1973. Oral zinc therapy in the control of infectious pododermatitis in young bulls. Vet. Rec., 93: 219– 222.

16.Deluyker, H.A., Gay, J.M., Weaver, L.D. and Azari, A.S. 1991. Change of milk yield with clinical diseases for a high producing dairy herd. J. Dairy Sci., 74: 436-445.

17.Douglas, G.N., Overton, T.R., Bateman II, H.G., Dann, H.M. and Drackley, J.K. 2006. Prepartal plan of nutrition, regardless of dietary energy source, affects periparturient metabolism and dry matter intake in Holstein cows. J. Dairy Sci., 89: 2141- 2157.

18.Eicher, S.D., Lay D.C., Jr Arthington, J.D. and Schutz, M.M. 2013. Effects of rubber flooring during the first 2 lactations on production, locomotion, hoof health, immune functions, and stress. J. Dairy Sci., 96: 3639–3651.

19.Fitzgerald, T., Norton, B.W., Elliot, R., Podlich, H. and Svendsen, O.L. 2000. The influence of long-term supplementation with biotin on the prevention of lameness in pasture fed dairy cows. J. Dairy Sci., 83:3 38-344.

20.Frigg, M., Straub, O.C. and Hartmann, D. 1992. The bioavailability of supplemental biotin in cattle. Int. J. Vitam. Nutr. Res., 63: 122- 128.

21.Ganpule, S.P. 1987. Seasonal incidence of major health problems in an exotic herd. Indian J. Anim. Hlth., 26: 69–71.

22.Goff, J.P. and Horst, R.L. 1997. Effects of the addition of potassium or sodium, but not calcium, to prepartum rations on milk fever in dairy cows. J. Dairy Sci., 80: 176-186.

23.Goff, J.P. and Stabel, J.R. 1990. Decreased plasma retinol, alphatocopherol, and zinc concentration during the periparturient period: effect of milk fever. J. Dairy Sci., 73: 3195-9.

24.Green, L.E., Hedges, V.J., Schukken, Y.H., Blowey, R.W. and Packington, A.J. 2002. The impact of clinical lameness on the milk yield of dairy cows. J. Dairy Sci., 85: 2250–2256.

25.Green, L.E., Borkert, J., Monti G. and Tadich, N. 2010. Associations between lesion-specific lameness and the milk yield of 1635 dairy cows from seven herds in the Xth region of Chile and implications for management of lame dairy cows worldwide. Anim. Welf., 19: 419–427.

26.Griffiths, L.M., Loeffler, S.H., Socha, M.T., Tomlinson, D.J. and Johnson, A.B. 2007. Effects of supplementing complexed zinc, manganese, copper and cobalt on lactation and reproductive performance of intensively grazed lactating dairy cattle on the South Island of New Zealand. Anim. Feed. Sci. Tech., 137: 69-83.

27.Grohn, Y.T., Erb, H.N., McCulloch, C.E. and Saloniemi, H.S. 1990. Epidemiology of reproductive disorders in dairy cattle: associations among host characteristics. Prev. Vet. Med., 8: 25–39.

28.Hedges, J.1., Blowey, R.W., Packington, A.J., O’ Callaghan, C.J and Green, L.E. 2001. A longitudinal field trial of the effect of biotin on lameness in dairy cows. J. Dairy Sci., 84(9): 1969- 75.

29.Herdt, T.H. 2000. Ruminant adaptation to negative energy balance. Influences on the etiology of ketosis and fatty liver. Vet. Clin. North Am. Small Anim. Pract., 16: 215-30.

30.Hernandez, J. and Shearer, J.K. 2000. Efficacy of oxytetracycline for treatment of papillomatous digital dermatitis lesions on various anatomic locations in dairy cows. J. Am. Vet. Med. Assoc., 216: 1288–1290.

31.Higuchi, H. and Nagahata, H. 2001. Relationship between serum biotin concentration and moisture content of the sole horn in cows with clinical laminitis or sound hooves. Vet. Rec., 148: 209–210.

32.Higuchi, H., Maeda, T., Kawai, K., Kuwano, A., Kasamatsu, M. and Nagahata, H. 2003. Physiological changes in the concentrations of biotin in the serum and milk and in the physical properties of the claw horn in Holstein cows. Vet. Res. Commun., 27: 407–413.

33.Hirst, W.M., Murray, R.D., Ward, W.R. and French, N.P. 2002. A mixed effects time-to-event analysis of the relationship between first-lactation lameness and subsequent lameness in dairy cows in the UK. Prev. Vet. Med., 54: 191-201.

34.Hoblet, K.H. and Weiss, W. 2001. Metabolic hoof horn disease, Claw horn disruption. Vet. Clin. N. Am-Food A., 17: 111-127.

35.Hochstetter, T. 1998. Horn quality of the bovine hoof under the influence of biotin supplementation. DVM Inaugural Dissertation. Journal #2176. Free University of Berlin, Germany.

36.Ingraham, R.H. and Kappel, L.C. 1988. Metabolic profile testing. Vet. Clin. N. Am-Food A., 4: 391.

37.Johnston, L.A. and Chew, B.P. 1984. Peripartum changes of plasma and milk vitamin A and β-carotene among dairy cows with or without mastitis. J. Dairy Sci., 67: 1832-1840.

38.Janovick, N.A., Boisclair, Y.R. and Drackley, J.K. 2011. Prepartum dietary energy intake affects metabolism and health during the periparturient period in primiparous and multiparous Holstein cows. J. Dairy Sci., 94: 1385-1400.

39.Kilic., Nuh, Ceylan., Ahmet Serin., Ilker. and Gokbulut, Cengiz. 2007. Possible interaction between lameness, fertility, some minerals, and vitamin E in dairy cows. B. Vet. I. Pulawy., 51: 425 -429.

40.Lawrence, R.J., Elliott R., Norton, B.W., Thoefner, M.B., Loxton I. and Webber, G. 2008. Influence of biotin supplementation on hoof growth and integrity in long-fed F1 Wagyu/Black Angus feedlot steers of known genotype. Austral. J. Exp. Agri., 48(5): 615-620.

41.LeBlanc, S.J. 2010. Monitoring metabolic health of dairy cattle in the transition period. J. Reprod. Dev., 56: S29-S35.

42.Lischer, Ch. J., Hunkeler, A., Geyer H. and Ossent, P. 1996. The effect of biotin in the treatment of uncomplicated claw lesions with exposed corium in dairy cows. Part II: The healing process in supplemented animals. In: Proceeding of 9th International Symposium. Disorders Ruminant Digit Int. Conf. Lameness Cattle at Koret School of Veterinary Medicine, Rehovot, Israel, pp. 31.

43.Maiti, S.K., Parai, T.P. and Nautiyal, L.P. 1996. Incidence of foot disorders in an organized dairy farm. Indian Vet. J., 73: 341–343.

44.Margerison, J.K., Winkler, B. and Stephens, G. 2002. The effect of locomotion score and lameness and on dry matter intake, feeding and general behaviour. In: Proceedings of XII Inter Symposium on Lameness in Ruminants. January 9-13, Florida, USA, pp. 407-410.

45.Melendez, P., Bartolome, J., Archbald, L.F. and Donovan, A. 2003. The association between lameness, ovarian cysts and fertility in lactating dairy cows. Theriogenology., 59: 927– 937.

46.Midla, L.T., Hoblet, K.H., Weiss, W.P. and Moeschberger, M.L. 1998. Supplemental dietary biotin for prevention of lesions associated with aseptic subclinical laminitis (Pododermatitis aseptic diffusa) in primiparous cows. Am. J. Vet. Res., 59: 733–738.

47.Minoccheri, F., Germana, G. and Negrini, F. 1977. Diffusion of some vitamins across the placenta in cattle: diffusion of pyridoxine, cobalamin and panthothenic acid. Zootenica Nutrizione Animals., 3: 209-215.

48.Moore, C.L., Walker, P.M.J., Winter, R., Jones, M.A. and Webb, J.M. 1989. Zinc methionine supplementation for dairy cows. Trans. Illinois. State. Acad. Sci., 82: 99–108.

49.Moore, D.A., Berry, S.L., Truscott, M.L. and Koziy, V. 2001. Efficacy of a non-antimicrobial cream administered topically for treatment of digital dermatitis in dairy cattle. J. Am. Vet. Med. Assoc., 19: 1435–1438.

50.Nayeri, A., Upah,N.C., Sucu, E., Sanz Fernandez, M.V., DeFrain J.M., Gorden P.J. and Baumgard, L.H. 2014. Effect of the ratio of zinc amino acid complex to zinc sulfate on the performance of Holstein cows. J. Dairy Sci., 97: 4392-4404.

51.Nobijaria, H.F. Amanloua, H. and Banadakyb, M.D. 2012. Effects of zinc supplementation on growth performance, blood metabolites and lameness in young Holstein bulls. J. Appl. Anim. Res., 40: 222-228.

52.Nocek, J.E. 1997. Bovine acidosis: Implications on laminitis. J. Dairy Sci., 80: 1005-1028.

53.NRC. 2001. Nutrient Requirements of Dairy Cattle, 7th, Natl. Acad. Press, Washington, DC.

54.Ospina, P.A., Nydam, D.V., Stokol, T. and Overton, T.R. 2010. Evaluation of non-esterified fatty acids and β-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. J. Dairy Sci., 93: 546-554

55.Potzsch, C.J., Hedges, V.J., Blowey, R.W., Packington, A.J. and Green, L.E. 2003. The impact of parity and duration of biotin supplementation on white line disease lameness in dairy cattle. J. Dairy Sci., 86(8): 2577-82

56.Roberts, C.J. and Baggott, D.G. 1982. Biotin experiments with dairy cattle. In: Proceedings of Roche Vitamin Symposium, London, pp. 13–20.

57.Rowlands, G.J., Lucey, S. and Russell, A.M. 1986. Susceptibility to disease in the dairy cow and its relationship with occurrences of other diseases in the current of preceding lactation. Prev. Vet. Med., 4: 3223-234.

58.Sharma, Neelesh and Upadhyay, S.R. 2009. Clinical Veterinary Medicine-II. New India Publishing, New Delhi, India.

59.Shipe, W.F., Senyk, G.F. and Fountain, K.B. 1980. Modified copper soap solvent extraction method for measuring free fatty acids in milk. J. Dairy Sci., 63: 193-198.

60.Singh, S., Prabhakar, S., Singh, S.S. and Ghumaqn, S.P.S. 1998. Incidence of lameness in dairy cows and buffaloes in Punjab State. Indian Vet. J., 75: 51–53.

61.Snedecor, G.W. and Cochran,W.G. 1994. Statistical methods, Iowa State University Press, Ames, Iowa, USA, 8th edition.

62.Sprecher, D.J., Hostetler, D.E. and Kaneene, J.B. 1997. A lameness scoring system that uses posture and gait to predict dairy cattle reproductive performance. Theriology., 47(6): 1179-87.

63.Van Saun, R.J., Todd, A. and Varga, G.A. 2005. Serum mineral concentrations and risk of periparturient disease. Protocol Am. Assoc. Bov. Pract., 38: 178-179.

64.Van Saun, R.J. 2006. Metabolic Profiles for Evaluation of the Transition Period. Proc. Am. Assoc. Bov. Pract., 39.

65.Zhang, Z., Liu, G., Li, X., Gao, L., Guo, C., Wang, H. and Wang. Z. 2010. Evaluation of the change of serum copper and zinc concentrations of dairy cows with subclinical ketosis. Biol. Trace Elem. Res., 138: 8-12.

66.Zinn, R.A., Owens, F.N., Stuart, R.L., Dunbar, J.R. and Norman, B.B. 1987. B-Vitamin supplementation of diets for feedlot calves. J. Animal Sci., 65: 267-77.